School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China. Guangzhou Institute of Cardiovascular Disease, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Department of Mathematics, Hong Kong Baptist University, Hong Kong, China. School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China. zlyu@hkbu.edu.hk. Consun Chinese Medicines Research Centre for Renal Diseases, School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. zlyu@hkbu.edu.hk.